Visual Field Characteristics of Type I Boston Keratoprosthesis Patients without Glaucoma.

PURPOSE To determine visual field findings in Boston Type 1-Kpro (BI-Kpro) patients without glaucoma. Characterize normal threshold values and global indices using standard automated perimetry and characterize visual field amplitude using Goldmann's manual perimetry. METHODS This cross-sectional prospective non-interventional study included patients (n=6 patients, 6 eyes) with BI-KPro who had normal optical coherence tomography and fundoscopic evaluation of the optic disc and retina. None had previous history of glaucoma. Visual acuity, reliable and reproducible standard automated perimetry (24-2 and 30-2) and manual perimetry examinations were obtained from all patients. Each patient answered the National Eye Institute Visual Function Questionnaire, and the results were correlated with visual field indices. RESULTS The mean visual acuity was 0.35±0.31 logMAR (0.84-0.10). All visual field's had good reliability indices. The standard automated perimetry mean deviation values were -7.25±3.63 decibels (dB) and -7.75±3.23 (24-2 and 30-2 values, respectively) while pattern standard deviation values were 2.72±0.82 and 3.30±1.13 (24-2 and 30-2, respectively). The manual visual field mean values of the four quadrants (superior, temporal, inferior, and nasal), were 39.7°±4.5°, 61.8°±6.2°, 54.0°±4.3°, and 48.2°±7.6°, respectively. We found a significant correlation between the VFQ-25 indexes of general sight and of close-range activities with the values [ZERO WIDTH SPACE][ZERO WIDTH SPACE]of Total deviation (TD) at 10°. VFQ-25 peripheral vision indexes also correlated significantly with values of Total deviation at 30° (outermost locations in the 30 degrees area). CONCLUSIONS Patients with BI-Kpro presented reliable and reproductive visual field measurements. We found a consistent reduction in visual field extension and a global sensitivity reduction in these patients. Despite visual field changes, our patients had good quality of life scores. Overall, these results could be useful to improve early glaucoma diagnosis and to follow-up BI-Kpro patients.