GW29-e1697 Activation of Farnesoid X Receptor enhances the survival of engrafted adipose-derived mesenchymal stem cells in mouse post-MI heart

The poor survival of engrafted stem cells in the ischemic environment limits their therapeutic efficacy for myocardial infarction (MI) treatment. Previously, we demonstrated that GW4064, an farnesoid X receptor (FXR) agonist, ameliorated post-MI cardiac dysfunction and remodeling. The current study