Materials based on protein-contained chitosan-g-oligo-/polylactide copolymers synthesized through mechanochemical approach

Abstract Solid-state mechanochemical approach to copolymer synthesis is a promising way to produce macromolecules combining properties and advantages of polymers of different nature. In addition to high efficiency and ecological benefits this synthetic route allows producing a relatively high amount of copolymers, which makes fabrication of the copolymer-based materials reasonable. Synthesis of amphiphilic natural/synthetic copolymers is especially promising in terms of their further use for formation of advanced materials for various applications, especially for biomedicine. This study highlights an effect of hydrophilic-hydrophobic balance of complex protein-contained chitosan-g-oligo-/polylactide copolymers on possibility to apply a range of material fabrication methods.