Keratoconus in Asian eyes at a tertiary eye care facility

Background: The purpose of this study was to assess the demographic variables, age at diagnosis, keratometry and slitlamp signs in keratoconus. Methods: Thirty-one patients with 61 keratoconic eyes were selected provided they met one of two criteria: 1. They had an irregular corneal surface, Vogt's striae, Fleischer's ring or apical sub-epithelial corneal scarring characteristic of keratoconus; 2. Corneal topography revealed an average simulated keratometry of more than 45.2 D, central corneal power higher than 47.2 D or infero-superior asymmetry greater than 1.4 D. The main outcome measures were demographic variables, age at diagnosis, disease severity on keratometry and biomicroscopic signs. Results: The patients' mean age at presentation was 20.2 ± 6.4 years. Based on average keratometry values, 67.2 per cent of eyes had severe and 32.8 per cent had moderate keratoconus. Eyes with severe keratoconus presented at a younger average age (18.8 ± 5.35 years) than moderate keratoconus (23.69 ± 8.07 years). Thirty-eight eyes (92.5 per cent) with severe and 13 eyes (65 per cent) with moderate keratoconus demonstrated biomicroscopic signs of keratoconus. Twenty eyes (32.7 per cent) demonstrated apical sub-epithelial cornea scarring and 95 per cent of these eyes had severe keratoconus. Conclusions: The majority of keratoconic eyes in Asian-Indian patients demonstrate the severe stage of the disease by the second decade.