Cyclic Equibiaxial Tensile Strain Alters Gene Expression of Chondrocytes via Histone Deacetylase 4 Shuttling

Chongwei Chen,Xiaochun Wei,Zhi Lv,Xiaojuan Sun,Shaowei Wang,Yang Zhang,Qiang Jiao,Xiaohu Wang,Yongping Li,Lei Wei

Cyclic Equibiaxial Tensile Strain Alters Gene Expression of Chondrocytes via Histone Deacetylase 4 Shuttling

2016

Chongwei Chen
Xiaochun Wei
Zhi Lv
Xiaojuan Sun
Shaowei Wang
Yang Zhang
Qiang Jiao
Xiaohu Wang
Yongping Li
Lei Wei

Objectives This paper aims to investigate whether equibiaxial tensile strain alters chondrocyte gene expression via controlling subcellular localization of histone deacetylase 4 (HDAC4).

Keywords:

Cell biology
Cytoplasm
Gene expression
Chondrocyte
Cell nucleus
Cellular differentiation
HDAC4
Subcellular localization
Strain (chemistry)
Biology
Molecular biology
Histone
Transfection

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