Analysis of lutein content in aqueous humor of patients with age-related cataract

Objective To detect the concentration of lutein in aqueous humor of patients with different levels of age-related cataract.Methods The concentration of lutein in aqueous humor of 34cases with age-related cataract patients was detected by high-performance liquid chromatography.Results The concentration of lutein in aqueous humor were (85.42±69.90,28.24±23.86,19.65±19.33)ng/mL in intumescent cataract group,mature cataract group and nuclear cataract group of patients respectively.The concentration of lutein in aqueous humor in tumescent cataract group were higher than in mature cataract group and nuclear cataract group patients,there was significant difference (P ＜ 0.05).There was no significant difference in mature cataract group and nuclear cataract group of patients (P ＞ 0.05).Conclusions With the increase of age-related cataract the lutein content in aqueous humor reduces,which indicate that the lutein content in aqueous humor is associated with cataract formation.It also provides a method of detecting the concentration of lutein in aqueous humor. Key words: Age-related cataract ;  Aqueous humor ;  Lutein ;  High-performance liquid chromatography ;