A New Cyclopeptide and Other Constituents from the Leaves of Zanthoxylum rigidumHumb. & Bonpl. ex Willd. (Rutaceae)

A new cyclopeptide, cyclozanthoxylane A (1), the lignans cis- and trans-methylpluviatolide, the flavonoid isoquercitrin, along with a mixture of benzoic and cinnamic acid derivatives, were isolated from the MeOH extract of the leaves of Zanthoxylum rigidum (Rutaceae). The structures of the compounds were determined on the basis of 1D- and 2D-NMR, and MS analysis. It is the first time that a natural cyclic peptide has been isolated from the genus Zanthoxylum.