Altered Cardiac Energetics and Mitochondrial Dysfunctionin Hypertrophic Cardiomyopathy

Sara Ranjbarvaziri,Kristina B. Kooiker,Mathew Ellenberger,Giovanni Fajardo,Mingming Zhao,Alison Schroer Vander Roest,Rahel A. Woldeyes,Tiffany T. Koyano,Robyn Fong,Ning Ma,Lei Tian,Gavin M. Traber,Frandics P. Chan,John Perrino,Sushma Reddy,Wah Chiu,Joseph C. Wu,Joseph Woo,Kathleen M. Ruppel,James A. Spudich,Michael Snyder,Kévin Contrepois,Daniel Bernstein

Altered Cardiac Energetics and Mitochondrial Dysfunctionin Hypertrophic Cardiomyopathy

2021

Background: Hypertrophic cardiomyopathy (HCM) is a complex disease partly explained by the effects of individual gene variants on sarcomeric protein biomechanics. At the cellular level, HCM mutatio...

Keywords:

cardiac energetics
Hypertrophic cardiomyopathy
individual gene
cellular level
complex disease
Medicine
Bioinformatics

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