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Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity.
2009
Disruption of the EGFR E884–R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity
Keywords:
- Cancer research
- Mitogen-Activated Protein Kinase 3
- Proto-Oncogene Proteins c-ret
- Kinome
- Proto-Oncogene Proteins c-kit
- Molecular biology
- COS cells
- Tyrosine-kinase inhibitor
- Mutation
- Proto-Oncogene Proteins c-met
- Biology
- Protein kinase A
- Gefitinib
- Epidermal growth factor receptor
- Erlotinib
- Protein kinase domain
- Carcinogenesis
- Correction
- Source
- Cite
- Save
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