Ex vivo Generation of Genetically Modified Macrophages from Human Induced Pluripotent Stem Cells

Mania Ackermann,Alexandra Kuhn,Jessica Kunkiel,Sylvia Merkert,Ulrich Martin,Thomas Moritz,Nico Lachmann

Ex vivo Generation of Genetically Modified Macrophages from Human Induced Pluripotent Stem Cells

2017

Mania Ackermann
Alexandra Kuhn
Jessica Kunkiel
Sylvia Merkert
Ulrich Martin
Thomas Moritz
Nico Lachmann

Background: Pluripotent stem cells, including induced pluripotent stem cells (iPSCs), have the capacity to differentiate towards all three germ layers and have been highlighted as a

Keywords:

Immunology
Induced pluripotent stem cell
Cell biology
Genetically modified organism
Germ layer
Stem cell
Haematopoiesis
Ex vivo
Induced stem cells
Genetic enhancement
Biology
Molecular biology
Transgene
Regenerative medicine
Viral vector
Expression cassette

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