Unusual Adaptive Optics Findings in a Patient With Bilateral Maculopathy

Over the past decade there has been a rapid evolution in our ability to noninvasively image the living human retina. Of particular interest is adaptive optics (AO), a technique that corrects for the eye’s monochromatic aberrations and allows nearly diffraction-limited imaging of the retina.1 There is increasing clinical application of AO imaging2–5 owing to the ability to resolve retinal pathological changes on a cellular level, although the future of AO imaging for clinical diagnosis is not clear. Of particular value in determining the potential diagnostic role of AO are cases in which the standard clinical picture is unclear. Here we describe a patient with bilateral progressive vision loss where AO imaging and optical coherence tomography (OCT) contributed to our understanding of the structural abnormalities associated with the visual dysfunction.