Biofabricated Humanized Insulin Producing Neo-Organs Generates Secondary Neo-Organoids Through Ectopic Transplantation
2019
Introduction
Developing transplantable humanized endocrine grafts for long-term management of disorders like uncontrolled diabetes mellitus has been one of the most challenging concerns in tissue and organ bioengineering. Hence, we aimed to develop bio/immune compatible and transplantable humanized insulin producing neo-organs through biofabrication of rat spleen which acts as secondary neo-organoid after ectopic transplantation.
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