연구논문 : 자두(홍로센, 헐리웃) 과피 열수추출물의 항산화능과 피부미백 효능 비교

This study was conducted to evaluate the antioxidative ability and whitening efficacy of peel`s water extracts from hongrosen (HR) and hollywood (HW) using in vitro tests or melan-a cells. In the antioxidative ability, the total polyphenol contents of HR and HW were 3.2 and 3.9 mg/g, respectively. The total flavonoid contents of HR and HW were 1.1 and 1.8 mg/g, respectively. The electron donating abilities of HR and HW at 1,000 μg/mL concentration were 12.2 and 13.2%, respectively. The ABTS radical scavenging activities of HR and HW at 1,000 μg/mL concentration were 45.0 and 60.2%, respectively. The SOD-like activities of HR and HW at 1,000 μg/mL concentration were 31.0 and 46.3%, respectively. In the whitening efficacy tests using melan-a cells, the maximum permissible level for HR and HW was ascertained over 200 μg/mL. For the melanin synthetic abilities at 50 μg/mL concentration, the arbutin, HR and HW significantly (p<0.05) reduced by 23.4, 16.4 and 28.5%, respectively, than the control. For the intra cellular tyrosinase activities at 50 μg/mL concentration, the arbutin, HR and HW significantly (p<0.05) reduced by 17.2, 10.9 and 9.0%, respectively, than the control. For the cell-extracted tyrosinase activities at 50 μg/mL concentration, the arbutin, HR and HW significantly (p<0.05) reduced by 47.5, 31.9 and 47.5%, respectively, than the control. Taken the results in together, peel`s water extracts from hongrosen and hollywood effectively inhibited melanin synthesis via inhibiting tyrosinase activity. The peel of hollywood had higher whitening efficacy than those of hongrosen and arbutin. Therefore, peel of hollywood can be used as the functional natural material for the whitening cosmetics.