Mussel-inspired adhesive and polypeptide-based antibacterial thermo-sensitive hydroxybutyl chitosan hydrogel as BMSCs 3D culture matrix for wound healing
2021
Abstract Hydrogels have gained great attentions as wound dressing. Binding to the tissue and preventing wound infection were the basic requirements for an “ideal dressing”. We employed L-DOPA and e-Poly-L-lysine to modify thermo-sensitive hydroxybutyl chitosan (HBC) to obtain (L-DOPA) - (e-Poly-L-lysine)-HBC hydrogels (eLHBC). The eLHBC exhibited an almost 1.5 fold (P
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