Carboxymethyl chitosan nanoparticles loaded with bioactive peptide OH-CATH30 benefit nonscar wound healing

Tongyi Sun,Bo Zhan,Weifen Zhang,Di Qin,Guixue Xia,Huijie Zhang,Meiyu Peng,Sheng-an Li,Yun Zhang,Yuanyuan Gao,Wen-Hui Lee

Carboxymethyl chitosan nanoparticles loaded with bioactive peptide OH-CATH30 benefit nonscar wound healing

2018

Tongyi Sun
Bo Zhan
Weifen Zhang
Di Qin
Guixue Xia
Huijie Zhang
Meiyu Peng
Sheng-an Li
Yun Zhang
Yuanyuan Gao
Wen-Hui Lee

Background Nonscar wound healing is a desirable treatment for cutaneous wounds worldwide. Peptide OH-CATH30 (OH30) from king cobra can selectively regulate the innate immunity and create an anti-inflammatory micro-environment which might benefit nonscar wound healing.

Keywords:

Combinatorial chemistry
Materials science
Nanoparticle
Biochemistry
Wound healing
Carboxymethyl-chitosan
Peptide
Chitosan
Granulation tissue
Cytotoxicity
Cell migration
Cytokine
Pharmacology
Drug delivery

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