DNA Hybridization Detection based on Plasmonic Photonic Crystal Fiber

A novel design of surface plasmon (SP) photonic crystal fiber (PCF) for DNA hybridization detection is proposed and analyzed. The suggested biosensor relies on plasmonic D-shaped PCF configuration. Accordingly, the core guided mode in the silica core is coupled with the SP mode near the plasmonic layer. The resonance wavelength is sensitive to the DNA hybridization process. Therefore, the suggested bio-sensor is studied to maximize the DNA hybridization detection sensitivity by adjusting the structural geometrical parameters. The numerical results are obtained using full vectorial finite element method with perfectly matched layer boundary condition and non-uniform meshing capabilities. The reported Dshaped PCF offers high wavelength sensitivity of 405.4 nm/RIU with a corresponding amplitude sensitivity of 5.65 RIU−1. Consequently, the applications based on DNA classification can be potentially implemented by the reported biosensor.