Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells

Fadi J. Najm,Angela M. Lager,Anita Zaremba,Krysta Wyatt,Andrew V. Caprariello,Daniel C. Factor,Robert T. Karl,Tadao Maeda,Robert H. Miller,Paul Joseph Tesar

Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells

2013

Fadi J. Najm
Angela M. Lager
Anita Zaremba
Krysta Wyatt
Andrew V. Caprariello
Daniel C. Factor
Robert T. Karl
Tadao Maeda
Robert H. Miller
Paul Joseph Tesar

Two studies show direct conversion of mouse embryonic fibroblasts to oligodendrocyte progenitor cells capable of generating myelinating oligodendrocytes.

Keywords:

Neural stem cell
Endothelial stem cell
Adult stem cell
Stem cell
Cellular differentiation
Reprogramming
Transdifferentiation
Molecular biology
Induced stem cells
Biology
Embryonic stem cell
Cell biology
Immunology

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