Investigating Retinal Toxicity of a Lutein-Based Dye in a Model of Isolated and Perfused Bovine Retina

Purpose Retidyne™ is a new lutein-based dye for internal limiting membrane staining. It uses the intrinsic staining characteristics of lutein which is already known to act as an antioxidant and blue-light filter in the human retina. We investigated retinal tolerance to different staining times measured by the electroretinogram (ERG) of an isolated and perfused retina whole mount.