Chitosan/bioactive glass coatings as a protective layer against corrosion of nanocrystalline titanium under simulated inflammation

Abstract Hydrogen peroxide (H2O2), which is produced during inflammation directly after the insertion of an implant, accelerates the corrosion process of Ti-based materials such as nanocrystalline bulk titanium. For this reason, there is a need to provide additional corrosion protection in the initial period following implantation. Coatings based on chitosan/bioactive glass were obtained by electrophoretic deposition (EPD) on nanocrystalline Ti. Results indicated that homogeneous, crack-free composite chitosan/bioactive glass EPD coatings effectively increased the resistance of nanocrystalline titanium to dissolution induced by H2O2.