Cefuroxime axetil film-coated tablets and preparation method thereof

2016 
The invention relates to cefuroxime axetil film-coated tablets and a preparation method thereof. The cefuroxime axetil film-coated tablets are composed of, by weight, 28-32 parts of cefuroxime axetil, 10-13 parts of microcrystalline cellulose, 6-8 parts of crosslinked sodium carboxymethyl cellulose, 2-3 parts of citric acid, 2-3 parts of sodium hydrogen carbonate, 1-2 parts of lauryl sodium sulfate, 1-2 parts of talcum powder and 0.5-2 parts of silicon dioxide. The problem of long disintegrating time of the cefuroxime axetil film-coated tablets is solved, dissolution rate is obviously increased, improving of dissolvability of the cefuroxime axetil film-coated tablets is guaranteed, drug quality is guaranteed, production cost is lowered, and production efficiency is improved. Bioavailability of the cefuroxime axetil tablets in human body is improved directly, drug treatment effect is improved, and drug dosage is lowered.
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