EEG and spectral analysis in HIV immunocompetent patients free from clinical CNS impairment. A follow-up study in 20 cases.

Twenty HIV immunocompetent subjects without neurological symptoms were studied by EEG and spectral EEG analysis over a period of 6-16 months. 40% of them showed mild diffuse changes in background activity on basal evaluation, but the appearance of neurological symptoms and the evolution of clinical picture seemed unrelated to the presence of aspecific EEG and spectral analysis changes. As most of them were oppiate abusers, these findings could be ascribed to the long-term drug use.