A novel chitosan-hydrogel-based nanoparticle delivery system for local inner ear application.

Shayanne A. Lajud,Danish A. Nagda,Peter Qiao,Nobuaki Tanaka,Alyssa Civantos,Rende Gu,Zhiliang Cheng,Andrew Tsourkas,Bert W. O'Malley,Daqing Li

A novel chitosan-hydrogel-based nanoparticle delivery system for local inner ear application.

2015

Shayanne A. Lajud
Danish A. Nagda
Peter Qiao
Nobuaki Tanaka
Alyssa Civantos
Rende Gu
Zhiliang Cheng
Andrew Tsourkas
Bert W. O'Malley
Daqing Li

Hypothesis A chitosan-hydrogel-based nanoparticle (nanohydrogel) delivery system can be used to deliver therapeutic biomaterials across the round window membrane (RWM) into the inner ear in a mouse model.

Keywords:

Nanoparticle
Round window
Chitosan
Inner ear
Biocompatible material
Anatomy
Perilymph
Medicine
Biomedical engineering
Middle ear
Liposome
Surgery
In vivo

Correction
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