A direct link of the Mos–MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs

Vertebrate oocytes are arrested in meiosis II until fertilization. This is one of two papers that link two previously known regulators of this arrest: the kinase Rsk that is activated by the Mos–MAPK pathway, directly phosphorylates Xerp1/Emi2 and thereby promotes its ability to inhibit the anaphase promoting complex APC/C.