Axially Chiral Synthons for Dendrimer Synthesis

Axially chiral synthons for chiral dendrimer construction based on 2,2'-dihydroxy-1,1'-binaphthalene-3,3'-dicarboxylic acid were prepared, namely, chiral connecting units ( 3 , 6 , 8 ), chiral branching units ( 10 , 12 , 14 ), and chiral surface units ( 5 , 17 ). Regioselective chloromethylation of methyl 3'-acetoxymethyl-2,2'-dimethoxy-1,1'-binaphthalene-3-carboxylate ( 7 ) was also studied.