Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

Junke Zheng,Masato Umikawa,Changhao Cui,Jiyuan Li,Xiaoli Chen,Chaozheng Zhang,HoangDinh Huynh,Xunlei Kang,Robert Silvany,Xuan Wan,Jingxiao Ye,Alberto Puig Cantó,Shu-Hsia Chen,Huan-You Wang,E. Sally Ward,Cheng Cheng Zhang

Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

2012

Junke Zheng
Masato Umikawa
Changhao Cui
Jiyuan Li
Xiaoli Chen
Chaozheng Zhang
HoangDinh Huynh
Xunlei Kang
Robert Silvany
Xuan Wan
Jingxiao Ye
Alberto Puig Cantó
Shu-Hsia Chen
Huan-You Wang
E. Sally Ward
Cheng Cheng Zhang

The binding of angiopoietin-like proteins to immune-inhibitory receptors maintains ‘stemness’ of haematopoietic stem cells and supports leukaemia development.

Keywords:

Myeloid-Lymphoid Leukemia Protein
Stem cell
Cell division
Cellular differentiation
Cell biology
HEK 293 cells
Leukemia
Haematopoiesis
Biology
Receptor
LILRB2
Adult stem cell
Cancer cell

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