Influence of CD38/PD1 co-expression on T cell subsets in HIV-TB co-infection
2012
Background Excessive immune activation as indicated by CD38 expression is a characteristic feature of HIV progression. There are growing evidences suggesting that immune inhibitory signals such as PD1 expression also play an important role in progression of the disease. However, the relationship between these positive (CD38) and negative (PD1) immune signals on T cells in HIV-TB co-infection has not been studied in detail so far.
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