ИММУНОХИМИЧЕСКИЕ СВОЙСТВА ЕСТЕСТВЕННЫХ АНТИТЕЛ К ФИЗИОЛОГИЧЕСКИ АКТИВНЫМ СОЕДИНЕНИЯМ

The review presents data related to the new direction of research on factors of the humoral immunity – natural antibodies which are produced in normal cells in the absence of antigenic stimulation. The questions of the survey methodology immunochemical properties of natural antibodies. Studied previously participated antibodies in immune reactions supplemented facts regulatory action in the body, which is closely linked with their immunochemical properties. The results of determination of immunoglobulins of isotype IgM, IgG, IgA class, their specifi city and affi nity to self antigens in the range 10 –5 –10 –8 M. analyzed part of the immune system to homeostasis by interacting with the biologically active molecules organism neural and humoral nature . Discussed the results of experiments that demonstrate the role of natural antibodies in the protective mechanisms involved adaptation processes.