Plasmon-enhanced fluorescence of nanoparticle-dye-protein complex as perspective approach for increase in fluorescent labeling effectiveness

This paper describes detailed study of photoprocesses in bovine serum albumin, silver nanoparticles and Rhodamine 6G (R6G) dye complexes using plasmon-enhanced fluorescence effect. Fluorescence spectroscopy analysis of bovine serum albumin molecules in systems doped with silver nanoparticles and rhodamine 6G has been performed. The perspectives of plasmon-controlled photoprocesses in the model complexes for applications of modern physics and biophotonics were shown. Investigations both tryptophan and tyrosine fluorescence of BSA in the complex has been investigated. Experimental concentrations of protein, dye and nanoparticles at which a stable plasmon-enhanced fluorescence effect was observed. Results of the study can be applied for labeling and configuring drug delivery systems for investigation of small blood components investigation such as platelets.