Cell sheet having hyaluronic acid production ability and method for producing same
2012
On a cell culture support having a surface covered with a polymer that changes hydration force within a temperature range of 0-80°C, cells are cultured in a temperature zone in which the hydration force of the polymer is weak, in a state where, for example, the stem cell content has been increased. Thereafter, the cells are detached by changing the culture broth to a temperature at which the hydration force of the polymer becomes strong, thereby making it possible to obtain a cell sheet having a high ability to produce hyaluronic acid.
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