Impact of ABCB1 Variants on Neutrophil Depression: A Pharmacogenomic Study of Paclitaxel in 92 Women with Ovarian Cancer

Troels K. Bergmann,Charlotte Brasch-Andersen,Henrik Gréen,Mansoor Raza Mirza,Kristin Skougaard,Jessica Wihl,Nina Keldsen,Per Damkier,Curt Peterson,Werner Vach,Kim Brøsen

Impact of ABCB1 Variants on Neutrophil Depression: A Pharmacogenomic Study of Paclitaxel in 92 Women with Ovarian Cancer

2012

Troels K. Bergmann
Charlotte Brasch-Andersen
Henrik Gréen
Mansoor Raza Mirza
Kristin Skougaard
Jessica Wihl
Nina Keldsen
Per Damkier
Curt Peterson
Werner Vach
Kim Brøsen

The standard treatment for ovarian cancer in advanced stages is post-surgery treatment with taxane-platin chemotherapy. Despite an initial high response rate, most patients eventually relapse. The ...

Keywords:

Biochemistry
Prospective cohort study
Ovarian cancer
Oncology
Pharmacogenetics
Standard treatment
Paclitaxel
Medicine
Immunology
Response rate (survey)
Internal medicine
Chemotherapy
Docetaxel

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