Neural crest stem cells increase beta cell proliferation and improve islet function in co-transplanted murine pancreatic islets
2009
Aims/hypothesis
Long-term graft survival after islet transplantation to patients with type 1 diabetes is insufficient, necessitating the development of new strategies to enhance transplant viability. Here we investigated whether co-transplantation of neural crest stem cells (NCSCs) with islets improves islet survival and function in normoglycaemic and diabetic mice.
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