Photodynamic therapy in a case of polypoidal choroidal vasculopathy associated with choroidal nevus.

PURPOSE: The purpose of this study was to report the clinical findings and management of a case of polypoidal choroidal vasculopathy associated with choroidal nevus. METHODS: A 59-year-old woman with a subfoveal vascular network with polypoidal lesions associated with choroidal nevus was treated with photodynamic therapy. The initial visual acuity was 1/60. Treatment was performed according to identical parameters to those used for choroidal neovascularization secondary to age-related macular degeneration and was repeated 3 months after the first application. The patient was prospectively followed with optical coherence tomography, fluorescein angiography, and indocyanine angiography. RESULTS: After the second treatment, total occlusion of the polypoidal lesions was observed but the vascular network remained still patent. During the 5-year follow-up, no recurrence was observed and the visual acuity rose to 1/10. CONCLUSION: In our experience, photodynamic therapy had positive results and this indicates the possibility that it could be a useful tool to manage these lesions and to improve their prognosis.