Intermediate uveitis complicated by choroidal granuloma following subretinal neovascular membrane: case reports

Choroidal neovascularization is a very rare complication in intermediate uveitis. A 27-year-old female patient diagnosed with intermediate uveitis two years ago. She presented with 20/200 visual acuity, snowballs, snowbanks, and macular cystoid edema in the right eye observed by fluorescein and optical coherence tomography (OCT). Photocoagulation was performed in the inferior peripheral retina in both eyes. The patient refused to undergo the prescribed clinical treatment. She returned twelve months later presenting with count fingers visual acuity, dry retina and subretinal macular pigmented granuloma observed on OCT. A 15-year-old female patient with decreased visual acuity of 20/400 in the right eye for eight days. She presented with bilateral vasculitis and papilitis, in the right eye, hemorrhage and extramacular subretinal neovascular membrane were observed on fluorescein and OCT. She was treated with 40 mg prednisone and intravitreous injection of 1.25 mg bevacizumab. Five months later she presented with 20/50 visual acuity, and extramacular granuloma observed on OCT. The formation of subretinal granuloma in intermediate uveitis is a possibility when complicated by subretinal neovascular membrane.(AU) Neovascularizacao de coroide e uma complicacao muito rara na uveite intermediaria(1). Paciente feminino, 27 anos, com diagnostico de uveite intermediaria dois anos atras. Apresentava acuidade visual de 20/200, "snowballs", "snowbanks" e edema macular cistoide no olho direito observado na angiofluoresceinografia (AGF) e tomografia de coerencia optica (OCT). Fotocoagulacao foi realizada na retina periferica inferior em ambos os olhos. A paciente recusou a submeter-se ao tratamento clinico prescrito. Ela retornou doze meses mais tarde apresentando acuidade visual de conta dedos, retina sem edema e granuloma sub-retiniano macular observado no OCT(2). Paciente feminino, 15 anos, com diminuicao da acuidade visual no olho direito (20/400) ha oito dias. Apresentava vasculite e papilite em ambos os olhos, no olho direito, hemorragia e membrana neovascular sub-retiniana observada na AGF e OCT. Foi tratada com 40 mg de prednisona e injecao intra-vitreo de bevacizumab (1,25 mg). Cinco meses depois, apresentou acuidade visual de 20/50 e granuloma extramacular observada no OCT. A formacao de granuloma sub-retiniano na uveite intermediaria e uma possibilidade quando complicada por membrana neovascular sub-retiniana.(AU)