Cellular compatibility of type collagen I scaffold and human adipose-derived stem cells

Objective To study the cellular compatibility of type I collagen scaffold and human adipose-derived stem cells (ADSCS)in order to explore appropriate scaffold materials for adipose tissue engineering. Methods The morphology and function of the ADSCS were observed by inverted phase contrast microscope, scanning electron microscope and XTT assay when cocultured type I collagen scaffold with ADSCS in vitro. Cells adhesive rates were also calculated. Result ADSCS were able to attach, grow and proliferate well on the scaffolds. Conclusion collagen I scaffold exhibits excellent cellular compatibility and can be used as a vehicle for adipose tissue engineering.