Basic Science of Liver Cancer Stem Cells and Hepatocarcinogenesis

The basic science of liver cancer stem cells (LCSCs) and hepatocarcinogenesis is best understood by familiarity with the increasingly complex epidemiology of hepatocellular carcinoma (HCC), with the still unknown cell origin(s) of HCC, with the anatomy and function of the liver lobule and with the historical and some novel methods for the study and identification of adult tissue stem cells and LCSCs.