Application of the rutin sodium in Alzheimer disease is prevented

2018 
The invention discloses application of the rutin sodium in Alzheimer disease is prevented, and belong to field of medicaments.The present invention is prepared rutin sodium, overcomes the problem of rutin dissolubility is poor by the way that rutin is dissolved in sodium hydroxide solution.And further by carrying out water maze laboratory to APP/PS1 transgenic mices (chronic AD models) and 5XFAD transgenic mices (acute AD models), demonstrating rutin sodium all has the function of two kinds of mouse to improve Spatial memory ability.This shows that rutin or derivatives thereof has AD apparent preventive and therapeutic action.
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