Dissolution detection method of nitrendipine and atenolol compound composition
2008
The invention provides a method for measuring the dissolution of a nitrendipine and atenolol compound composition through a high-efficiency liquid chromatography method. The method comprises the following steps of: by using a lauryl sodium sulfate solution as a dissolution medium, dissolving out the compound composition; and by using a mixture of methanol and a diammonium hydrogen phosphate solution as a mobile phase, measuring the dissolution amount of nitrendipine and atenolol through the high-efficiency liquid chromatography method by using a detection wavelength of 235nm.
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