HPLC를 이용한 기능성 원료 지표성분으로서 장수 오미자 분말 중 Schizandrin의 분석법 개발

We studied the development of schizandrin as a marker compound in Jangsu Omija. Schizandrin was validated for its LOD (limit of detection), LOQ (limit of quantitation), precision, accuracy, and recovery by HPLC relative to Omija powder. It showed a high linearity in the calibration curve with a coefficient of correlation (R²) of 0.9990. The LOD and LOQ were 0.2 μg/mL and 0.5 μg/mL, respectively. The intra- and inter-day precision of schizandrin calibration standards was 0.06～0.66% and 0.13～1.19%, respectively, and the intra- and inter-day accuracy of schizandrin was 98.35～103.30% and 98.35～103.00%, respectively. Overall, schizandrin was validated through our analytical methods as a marker compound in Jangsu Omija.