Polymorphisms and expression of inflammasome genes are associated with the development and severity of rheumatoid arthritis in Brazilian patients

C. Addobbati,Heidi Lacerda Alves da Cruz,José Eduardo Adelino,Amanda Luíze Melo Tavares Ramos,Thiago Sotero Fragoso,Alexandre Domingues,Ângela Luiza Branco Pinto Duarte,R.D.R. Oliveira,Paulo Louzada-Junior,Eduardo A. Donadi,Alessandra Pontillo,Jaqueline de Azevêdo Silva,Sergio Crovella,Paula Sandrin-Garcia

Polymorphisms and expression of inflammasome genes are associated with the development and severity of rheumatoid arthritis in Brazilian patients

2018

C. Addobbati
Heidi Lacerda Alves da Cruz
José Eduardo Adelino
Amanda Luíze Melo Tavares Ramos
Thiago Sotero Fragoso
Alexandre Domingues
Ângela Luiza Branco Pinto Duarte
R.D.R. Oliveira
Paulo Louzada-Junior
Eduardo A. Donadi
Alessandra Pontillo
Jaqueline de Azevêdo Silva
Sergio Crovella
Paula Sandrin-Garcia

Objective In the present study, we analyzed the possible association of inflammasome gene variants and expression to rheumatoid arthritis (RA)’s development and severity in the Brazilian population.

Keywords:

Diabetes mellitus
Biochemistry
Immunology
Biology
Gene
Inflammasome
Rheumatoid arthritis
Autoimmunity
Single-nucleotide polymorphism
Population
NLRC4
Gene expression
Genetic association
Internal medicine
NLRP1
AIM2
Rheumatology

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