Nanoplasmonic Alloy of Au/Ag Nanocomposites on Paper Substrate for Biosensing Applications

Plasmonic alloy has attracted much interest in tailoring localized surface plasmon resonance (LSPR) for recent biosensing techniques. In particular, paper-based plasmonic substrates allow capillary-driven lateral flow as well as three-dimensional metal nanostructures, and therefore they become actively transferred to LSPR-based biosensing such as surface-enhanced Raman spectroscopy (SERS) or metal-enhanced fluorescence (MEF). However, employing plasmonic alloy nanoislands on heat-sensitive substrate is still challenging, which significantly inhibits broad-range tailoring of the plasmon resonance wavelength (PRW) for superior sensitivity. Here we report paper-based plasmonic substrate with plasmonic alloy of Au/Ag nanocomposites for highly sensitive MEF and SERS biosensing applications. The nanofabrication procedures include concurrent deposition of Au and Ag below 100 °C without any damage on cellulose fibers. The Au/Ag nanocomposites feature nanoplasmonic alloy with single plasmon peak as well as broad-r...