Regulation of Human IgE Production by Peripheral Blood Mononuclear Cells from Atopic Patients in Mice with Severe Combined Immunodeficiency

Mamoru lto,Go Matsuzaki,Shu Uno,Yuko Katakai,Matsunobu Suko,Sachio Endo,Hirokazu Okudaira

Regulation of Human IgE Production by Peripheral Blood Mononuclear Cells from Atopic Patients in Mice with Severe Combined Immunodeficiency

1992

Mamoru lto
Go Matsuzaki
Shu Uno
Yuko Katakai
Matsunobu Suko
Sachio Endo
Hirokazu Okudaira

Human peripheral blood mononuclear cells (PBMC) were transferred (i.p.) to severe combined immunodeficient (SCID) mice. PBMC from atopic donors developed both IgE and IgG synthesis, while only IgG syn

Keywords:

Immunology
Virology
Immunoglobulin E
Immune system
Adoptive cell transfer
Severe combined immunodeficiency
Humoral immunity
Atopy
House dust mite
Peripheral blood mononuclear cell
Biology
Ratón

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