The Use of Long-Term Culture Techniques to Study Peripheral Blood Stem Cells Before and After Autologous Transplantation

Autologous blood stem cells collected during the recovery phase after intensive chemotherapy are rich in progenitor cells, and, when infused into patients who have received myeloablative therapy, lead to rapid and durable hematopoietic reconstitution [6]. The rate of engraftment has been demonstrated to be correlated with the number of late progenitor cells infused [4].