Compound osseous tissue engineering stephanoporate stent material and preparation thereof

The invention discloses a porous support material in the tissue engineering of konjac glucan-mannan/ hydroxyapatite/chitosan combined bone, and a preparation thereof, pertaining to the technical field of bioengineering materials. Degradable biomaterials with good biocompatibility, such as konjac glucan-mannan, hydroxyapatite and chitosan, are adopted as basic raw materials and respectively prepared into konjac glucan-mannan solution and hydroxyapatite/chitosan composite powder suspension which are then mixed to prepare mixture gel. After aging, alkali elimination, freeze-drying of the mixturegel, the degradable porous support with regenerated and reparative konjac glucan-mannan/hydroxyapatite/chitosan combined bone tissues. Not only does the support material have simple preparation technology and low cost, but also the prepared degradable porous support has good compatibility with trauma parts. Cell tests and animal tests show that the support can be universally used in vivo (bone defect diseased region, etc.) and is multifunctional and antibacterial composite material with adjustable degradation rate in vivo and can promote and induce the repair of the bone defect.