Derived optically active piridobenzoxatina.

DERIVATIVE pyridobenzoxazine OPTICALLY ACTIVE represented by formula (I): wherein R HIGH 1 YR (squared), which can be equal or different, each represents an alkali GROUP SUPPLIED 1 to 6 carbon atoms, a group ALKALINE HALOGENATED PROVIDED 1 to 6 carbon atoms, a group HIDROXIALCALINO SUPPLIED 1 to 6 carbon atoms, or a group ALKOXIMETILO comprises 2 to 7 carbon atoms; R ELEVATED 3 represents an atom of hydrogen, a ALKALINE SUPPLIED 1 to 6 carbon atoms, an acyl group comprises 2 to 7 carbon atoms, a halogen substituted or GROUP ALKILOXICARBONILO unsubstituted comprises 2 to 7 carbon atoms , phenylmethyloxycarbonyl GROUP OR A GROUP WHICH phenylmethyloxycarbonyl phenyl moiety is substituted with a halogen atom, a nitro group or ONE METHOXY; R ELEVATED 4 represents a methyl or fluoromethyl Settings (BETA); R ELEVATED 5 represents an atom of hydrogen, an amino group, a hydroxyl, OR ONE METHYL a halogen atom; X represents a fluorine atom or chlorine atom, and a salt thereof. These compounds exhibit potent antimicrobial activity WITH BROAD SPECTRUM ANTIMICROBIAL PROPERTIES AND IMPROVED lipophilic.