Clinical significance of the thymidylate synthase, dihydropyrimidine dehydrogenase, and thymidine phosphorylase mRNA expressions in hepatocellular carcinoma patients receiving 5-fluorouracil-based transarterial chemoembolization treatment.

Hongyun Zhao,Yuanyuan Zhao,Ying Guo,Yan Huang,Suxia Lin,Cong Xue,Fei Xu,Yang Zhang,Liping Zhao,Zhihuang Hu,Li Zhang

Clinical significance of the thymidylate synthase, dihydropyrimidine dehydrogenase, and thymidine phosphorylase mRNA expressions in hepatocellular carcinoma patients receiving 5-fluorouracil-based transarterial chemoembolization treatment.

2013

Hongyun Zhao
Yuanyuan Zhao
Ying Guo
Yan Huang
Suxia Lin
Cong Xue
Fei Xu
Yang Zhang
Liping Zhao
Zhihuang Hu
Li Zhang

Purpose To determine whether 5-fluorouracil (5-FU) sensitivity is associated with the mRNA expressions of thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), and thymidine phosphorylase (TP) in patients with hepatocellular carcinoma (HCC) treated with 5-FU-based transarterial chemoembolization (TACE).

Keywords:

Thymidylate synthase
Fluorouracil
Thymidine phosphorylase
Hepatocellular carcinoma
Pathology
Dihydropyrimidine dehydrogenase
Messenger RNA
Medicine
in patient
Clinical significance

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