UTILISATION OF AN ELECTROCHEMILUMINESCENCE SENSOR FOR ATROPINE DETERMINATION IN COMPLEX MATRICES

A major challenge within forensic science is the development of accurate and robust methodologies which can be utilised on site for detection at crime scenes and can be used for analysing multiple sample types. The recent expansion of electro-chemical sensors to tackle this hurdle requires sensors that can undergo analysis without any pre-treatment. Given the vast array of samples that are submitted for forensic analysis, this can pose a major challenge for all electrochemical sensors including electrochemiluminescent (ECL) based sensors. Within this contribution, we demonstrate the capacity for an ECL based sensor to address this challenge and it’s potential to detect and quantify atropine from a wide range of samples directly from herbal material to spiked solutions. This portable platform demonstrates satisfactory analytical parameters with linearity across a concentration range of 0.75 µM to 100 µM, reproducibility of 3.0%, repeatability of 9.2% and a detection limit of ~ 0.75 µM. The sensor displays ...