Bubble detection on Left Atrium related with patent foramen ovale

Several illnesses such as paradoxical embolism, decompression sickness, migraine and cerebral ischemia are characterized by bubbles which might cross the septum wall between left and right atrium. In this study, we aimed to detect bubbles on echocardiographic frames which are segmented automatically using snakes method. In recent studies, analyzes are done on fixed ROIs and PFO grading as well. We conclude that our approach would give more accurate results for bubble detection and counting by taking account into entire Left Atrium (LA) areas.