Apolipoprotein A-I stimulates AMP-activated protein kinase and improves glucose metabolism
2007
Aims/hypothesis
In humans, one of the hallmarks of type 2 diabetes is a reduced plasma concentration of HDL and its major protein component, apolipoprotein A-I (APOA-I). However, it is unknown whether APOA-I directly protects against diabetes. The aim of this study was to characterise the functional role of APOA-I in glucose homeostasis.
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