Magnetic bead handling on-chip: new opportunities for analytical

This review describes recent advances in the handling and manipulation of magnetic particles in mi- crofluidic systems. Starting from the properties of magnetic nanoparticles and microparticles, their use in magnetic separation, immuno-assays, magnetic reso- nance imaging, drug delivery, and hyperthermia is dis- cussed. We then focus on new developments in magnetic manipulation, separation, transport, and detection of magnetic microparticles and nanoparticles in microflui- dic systems, pointing out the advantages and prospects of these concepts for future analysis applications.