A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents.

J. Jelinek,Joseph A Rafferty,R. Cmejla,Markus Hildinger,Dhanalakshmi Chinnasamy,Linda S Lashford,Wolfram Ostertag,Geoffrey P. Margison,Dexter Tm,Leslie J. Fairbairn,Christopher Baum

A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents.

1999

J. Jelinek
Joseph A Rafferty
R. Cmejla
Markus Hildinger
Dhanalakshmi Chinnasamy
Linda S Lashford
Wolfram Ostertag
Geoffrey P. Margison
Dexter Tm
Leslie J. Fairbairn
Christopher Baum

A novel dual function retrovirus expressing multidrug resistance 1 and O 6 -alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents

Keywords:

Virus
Progenitor cell
Cancer research
Methyltransferase
Molecular biology
Multiple drug resistance
Immunology
Stem cell
Retrovirus
Transduction (genetics)
Genetic enhancement
Biology
Doxorubicin
genetic transfer
K562 cells

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